Myocardial infarction: rapid ruling out in the emergency room

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Myocardial infarction: rapid ruling out in the emergency room

www.thelancet.com Vol 386 December 19/26, 2015 2449 Patients with symptoms of possible acute coronary syndrome make up a large proportion of people who present to emergency departments, where they undergo lengthy, intensive, and costly assessments. Yet few are fi nally diagnosed with an acute coronary syndrome. Improvements in methods to exclude acute coronary syndrome are needed to reliably re...

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Safe discharge from the cardiac emergency room with a rapid rule-out myocardial infarction protocol using serial CK-MB(mass).

OBJECTIVE To determine whether a new protocol, using a rapid and sensitive CK-MB(mass) assay and serial sampling, can rule out myocardial infarction in patients with chest pain and decrease their length of stay in the cardiac emergency room without increasing risk. DESIGN The combined incidence of cardiac death and acute myocardial infarction at 30 days, six months, and 24 months of follow up...

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Rapid Protocols to Rule out Myocardial Infarction.

Evidence Summary Cardiac troponin T and I are released into the bloodstream when cardiac muscle is damaged. Cardiac troponin tests have been available for decades and are the preferred biomarkers for the diagnosis of acute myocardial infarction (AMI).1 However, until recently, they lacked sensitivity in the first few hours following an acute myocardial injury. Therefore, AMI could not be ruled ...

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Rapid Diagnosis of Acute Myocardial Infarction

To improve the specificity of biochemical markers of myocardial infarction (MI) a method to measure cardiac troponin-I (CTn-I) was developed. CTn-I is a protein unique to cardiac muscle and is released after MI. Consecutive 150 patients admitted to the coronary care unit was studied. Value of CTn-I was determined in all samples. CTn-I concentration in the MI patients group was increased com...

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Optimal cut-off value for cardiac troponin I in ruling out Type 5 myocardial infarction.

OBJECTIVES The clinical classification of myocardial infarction (MI) into five types was introduced in 2007 as a component of the universal definition. A Type 5 MI was defined as a MI related to coronary artery bypass surgery. In a setting of patients undergoing elective coronary artery bypass grafting, we set out (i) to describe the pattern of multiple serial cardiac troponin I (cTnI) measurem...

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ژورنال

عنوان ژورنال: The Lancet

سال: 2015

ISSN: 0140-6736

DOI: 10.1016/s0140-6736(15)00449-3